Facultade de Fisioterapia

Nanoparticle-enhanced liquid-phase microextraction

Authors: Carlos Bendicho, Isabel Costas Mora, Vanesa Romero, Isela Lavilla.

Journal: TrAC Trends in Analytical Chemistry, 68: 78-87, 05/2015

DOI: http://dx.doi.org/10.1016/j.trac.2015.02.007


Nanostructured materials play roles in different areas of analytical chemistry. Implementation of nanomaterials in liquid-phase microextraction results in a synergic combination yielding enhanced performance. Some significant examples include: carbon nanotubes for improving extraction efficiency; magnetic nanoparticles for retrieving ionic liquids or organic solvents; metal nanoprobes in a solvent microvolume for desalting and ionization in the analysis of proteins and peptides by matrix-assisted laser desorption/ionization-mass spectrometry; in situ generation of noble-metal nanoprobes for extraction of hydride-forming elements prior to their determination by atomic spectrometry; confinement of fluorescent nanoprobes in a microvolume of organic solvent, thereby integrating separation, preconcentration and analyte recognition within a single step; and, solid-phase extraction involving nanomaterials and liquid-phase microextraction in a sequential way. We provide insight into significant advances involving the joint use of nanomaterials and liquid-phase microextraction.