Facultade de Fisioterapia

Liquid-phase microextraction techniques within the framework of green chemistry

Authors: Francisco Pena-Pereira, Isela Lavilla, Carlos Bendicho

Journal: TrAC Trends in Analytical Chemistry, 29: 617-628, 08/2010

DOI: http://dx.doi.org/10.1016/j.trac.2010.02.016


This overview deals with the evolution of liquid-phase microextraction (LPME) techniques from their inception in mid-to-late 1990s. We describe and evaluate the most important developments towards implementing greener analytical methodologies focused on the use of less toxic extractant phases, clean energies combined with LPME techniques, new materials (e.g., monolithic silica and nanoparticles), automation of LPME methodologies and recent developments in hyphenation of LPME with a broad variety of analytical techniques.