Facultade de Fisioterapia

Liquid-phase microextraction approaches combined with atomic detection: A critical review

Authors: Francisco Pena-Pereira, Isela Lavilla, Carlos Bendicho

Journal: Analytica Chimica Acta, 669: 1-16, 06/2010

DOI: http://dx.doi.org/10.1016/j.aca.2010.04.050


Liquid-phase microextraction (LPME) displays unique characteristics such as excellent preconcentration capability, simplicity, low cost, sample cleanup and integration of steps. Even though LPME approaches have the potential to be combined with almost every analytical technique, their use in combination with atomic detection techniques has not been exploited until recently. A comprehensive review dealing with the applications of liquid-phase microextraction combined with atomic detection techniques is presented. Theoretical features, possible strategies for these combinations as well as the effect of key experimental parameters influencing method development are addressed. Finally, a critical comparison of the different LPME approaches in terms of enrichment factors achieved, extraction efficiency, precision, selectivity and simplicity of operation is provided.